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发布网友发布时间：2022-05-29 18:12

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热心网友时间：2023-11-01 11:26

[摘要] Abstract

目的：Purpose:

通过对南京地区33家医院2009～2011年抗真菌药物利用情况的分析，来评价近年来抗真菌药物治疗。
Evaluating the treatment by antifungal agents in recent years by means of an analysis of the cases in which 33 hospitals in Nanjing region used antifungal agents ring 2009-2011.

方法：Method

采用金额和用药频度分析及排序法进行药物利用分析。
Adopting an analysis of the currency amount and the frequency of taking medication as well as ranking method to analyze medicine utilization.

结果：Result:

1）抗真菌药物antifungal agent占总抗菌药物的总金额呈逐年增加趋势，其中2010年均增长率最高为16.9%。
The currency amount of antifungal agents which account for the total are increasing year after year, and thereinto the average rate of increase in 2010 was the topmost 16.9%.

2）抗真菌药物金额构成比最大的是深部抗菌药，尤其是*类Triazole药物，金额由2009年的3360.56万元增加到2011年的4418.43万元，年均增长率为14.66%，棘白霉素类药物年均增长率最大为18.67%。
The topmost composing rate of the currency amount of antifungal agents was the rate of Pars profunda antibacterials, especially the sort of Triazole, the currency amount of which increased from 33,605,600 Yuan in 2009 to 44,184,300Yuan in 2011 and the average increase rate per year of which is 4.66%. The topmost increase rate of the sort of echinocandin is 18.67%.

3）抗真菌药通用名金额排序中*类药物排在前列，伏立康唑的排名从2009年的第3位上升到2011年的第1位。
The sort of Triazole in the ranking of the generic name of antifungal agents is located in the front rank, and the ranking of voriconazole mounted into the first place in 2011 from the third in 2009.

4）厂家排名中，排在前几位的外企占绝大多数，也有国内企业如珠海亿邦至2011年上升至第3位。
Of the manufacture ranking, the foreign enterprises are overwhelming majority at the first places, only Zhuhai Yibang mounted to the third place in 2011.

5) 抗真菌药DDDs排序中，*类的氟康唑和伊曲康唑仍排在前列，浅部抗真菌药特比萘芬排名也居前。
Of the ranking in antifungal agent DDDs, the Fluconazole and Itraconazole in the sort of Triazole are still at the front rank; Terminating in pars superficial antifungal agents is ranked at front rank as well.

结论：Conclusion

1）2009～2011年南京地区33家医院抗真菌药物用药金额增长较为显著，抗深部真菌药物趋于选用*类，尤其是氟康唑及伊曲康唑，浅表真菌感染趋于使用特比萘芬，棘白霉素类药物使用率增长最为显著。
In 2009-2011, the currency amount of antifungal agents taking increased is relatively remarkable in the 33 hospitals in Nanjing region. Pars profunda antibacterials tended to choose Triazole, especially Fluconazole and Itraconazole; pars superficial epiphyte infection tended to use Terbinafin, and the rate of utilization of the sort of echinocandin was most remarkable.

2）进口药占据了主要市场，以美国辉瑞及西安杨森为代表。
Imported leechdom occupied the leading market and thereinto America Phize and Xi’an Yangsen are the representations.

3）金额排序与DDDs排序稍有区别的原因可能是*类药物伏立康唑价格偏高，以至于在DDDs排序中排在特比萘芬后面。
The cause of the slight difference of the ranking of currency amount and DDDs may be the price of voriconazole of the sort of Triazole is on the high side so that it ranked behind Terbinafine in the ranking of DDDs.

[关键词] Keywords

抗真菌药物 _—— antifungal agent；
药物利用 —— medicine utilization；
金额 —— currency amount；
DDD —— Dichloro-diphenyl-tricgloroethane
南京 —— Nanjing

热心网友时间：2023-11-01 11:27

[Abstract] Objective: Through the use of analysis of the situation in 33 hospitals in Nanjing from 2009 to 2011 antifungal, evaluation in recent years antifungal therapy. Methods: The amount and frequency of drug analysis and sorting method for drug utilization analysis. Results: 1) antifungal agents accounted for the total amount of antimicrobial drugs was increasing year by year, of which 2010 the average annual growth rate up to 16.9%. 2) of the amount of antifungal agents than is deep antimicrobial agents, especially triazole drugs, the amount of 33.6056 million yuan in 2009 to 44.1843 million yuan in 2011, the average annual growth rate of 14.66%, the spines white mold The average annual growth rate of the hormone drugs up to 18.67%. 3) antifungal generic triazole drugs in the amount of sorting the top the voriconazole ranking increased from three in 2009 to 2011, a. 4) manufacturers ranked in the top few foreign companies accounted for the vast majority of domestic enterprises, such as of Zhuhai billion state in 2011 rose to 3. 5) The antifungal the DDDs sort of triazoles fluconazole and itraconazole is still the top row, shallow antifungal special terbinafine ranked top. Conclusion: 1) 2009 2011 Nanjing 33 hospitals antifungal medication the amount of growth is more significant anti deep fungal drugs tend to choose the triazoles, especially fluconazole and itraconazole, superficial fungal infection tends to use special than naphthalene fun, white spines neomycin drug usage growth, the most significant. 2) imported drugs accounted for the major markets, as the representative of the United States, Pfizer and Xian-Janssen. 3) the amount of sort and DDDs sort of slightly different reason may be that the triazole drug voriconazole high prices, that in DDDs sort at the back of terbinafine.[Key words] antifungal; drug use; amount; of DDD Nanjing

热心网友时间：2023-11-01 11:27

[Abstract] Objective: through to the Nanjing area in 33 hospitals from 2009 to 2011 antifungal drug use analysis of the situation in recent years, to the evaluation of antifungal agents in the treatment of.Methods: the sum and DDDs analysis and sorting method of drug utilization analysis.Results: 1) antifungal drugs accounted for total amount of antimicrobial drugs increased year by year, of which 2010 annual growth rate for the highest 16.9%.2) antifungal drug amount proportion is the largest deep antibacterial drugs, especially the three azole drugs, amount from 33605600 yuan in 2009 to 44184300 yuan in 2011, an average annual growth rate of 14.66%, spike kitasamycin drugs to a maximum of 18.67% average annual growth rate.3) antifungal drug generic name in order of the amount of three triazole drug at the front row, voriconazole ranking from 2009 third to 2011 first.4) manufacturers in the ranking, the first several foreign invested enterprises accounted for the vast majority, there are domestic enterprises such as Zhuhai billion to the 2011 rising to third.5) antifungal drug DDDs sort of three triazole, fluconazole and itraconazole is still ranked in the forefront, shallow antifungal terbinafine ranking top.Conclusion: 1) in Nanjing from 2009 to 2011 in 33 hospitals of antifungal drugs is more significant amount of growth, resistance to fungal drugs tend to choose three triazole, fluconazole and itraconazole in particular, superficial fungal infections tend to use of terbinafine, spines kitasamycin drugs utilization rate of growth is the most significant.2) imported drugs to occupy the main market in the United States, Pfizer and Yang Sen as the representative of xi'an.3) the amount of sequencing and DDDs ranking slightly different may be the cause of three triazole drug voriconazole price is on the high side, so that in the DDDs ranking ranked terbinafine behind.
[Key words] antifungal drug; drug utilization; amount; DDD Nanjing

热心网友时间：2023-11-01 11:28

[abstract] objective: to nanjing area by 33 hospitals in 2009 ~ 2011 years of antifungal drugs, by the analysis of the evaluation of antifungal drugs in recent years. Methods: the amount and drug use frequency analysis and sorting method for the drug use analysis. Results: 1) antifungal drugs to total antimicrobial agents in the amount of the trend has increased year by year, of which 2010 annual growth rate up to 16.9%. 2) antifungal drugs constitute the largest amount than deep antibiotic, especially three azole drug, amount by 2009 the $33.6056 million increase in 2011 to 44.1843 million yuan, with an average annual growth rate of 14.66%, with the white drugs maximum annual growth rate of 18.67%. 3) antifungal drugs amount of generic sorting of three azole drug the top, the ranking voriconazole from the third place in 2009 rose to 2011 in the first place. 4) manufacturer rankings, the first several of the foreign enterprise in a majority, also the domestic enterprise such as zhuhai nations to 2011 she rose to third place. 5) antifungal drugs DDDs sort, three azole fluconazole itraconazole and was still the top, shallow antifungal drugs than naphthalene, Stevens also ranked the first. Conclusion: 1) 2009 ~ 2011 nanjing area hospitals and antifungal medication amount growth is significant, resistance to deep fungus drugs tend to choose three azole, especially fluconazole and itraconazole thiazole, superficial fungal infections tend to use than naphthalene, Finn, with the white of drugs utilization rate is the most significant growth. 2) haart occupy the central market, by American Pfizer and xian-janssen represented. 3) order and the amount DDDs sort of slightly different reasons may be three azole voriconazole drug prices high, in order that DDDs were ranked than naphthalene, Finn behind.
[key words] antifungal drugs; Drug use; Amount; DDD nanjing

热心网友时间：2023-11-01 11:28