发布网友 发布时间:2022-05-02 03:21
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热心网友 时间:2022-06-27 14:40
Investigation of associations between proteins encoded by genes in the human PPI (Protein-protein interaction) network has become one of the most effective approaches to elucidating the molecular mechanisms underlying the complex diseases. In the process of investigating these associations, most of them are done by similarity comparison of network topology of nodes in the PPI network. For example, measuring the topology similarity based on either the common neighbors, or the distance, between network nodes.