发布网友 发布时间:2022-07-12 19:28
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热心网友 时间:2023-10-19 17:20
1997年6月、 赣南师范学院理学学士
2004年6月,2007年6月 中科院福建物构所理学硕士、理学博士
2007年- 赣南师范学院,江西省有机药物化学重点实验室副教授
【研究领域与兴趣】
结构生物学与分子生物学蛋白晶体培养及蛋白质表达
【学术论文】
1. Huai, Q., Marzar, A. P., Kuo, A., Parry, G. C., Shaw, D. E., Callahan, J., Li Yongdong., Yuan, C.,Bian, C., Chen, L., Furie, B., Furie, B. C., Cines, D. B. & Huang, M. (2006). Structure of humanurokinase plasminogen activator in complex with its receptor. Science 311, 656-9
2. Li, Yongdong., Parry, G., Chen, L., Callahan, J. A., Mazar, A. P. & Huang, M. (2007). An anti-urokinase plasminogen activator receptor (uPAR) antibody: crystal structure and binding epitope. Journal of Molecular Biology 365. 1117-1129(IF: 5.23)
3. Li, Yongdong., Shi, X., Parry, G., Chen, L., Callahan, J. A., Mazar, A. P. & Huang, M. (2005). Optimization of crystals of an inhibitory antibody of urokinase plasminogen activator receptor (uPAR) with hydrogen peroxide and low protein concentration Protein Pept Lett 12. 655-8 (IF: 0.84)
4. Rao, Y., Bian, C., Yuan, C., Li, Yongdong., Chen, L., Ye, X., Huang, Z. & Huang, M. (2006). An open conformation of swith I revealed by Sar1-GDP crystal structure at low Mg(2+). Biochem Biophy Res Commun 348 (3). 908-15. (IF: 3.0)
5. Shi, X., Li, Yongdong., Bian, C., Zhao, G. & Huang, M. (2005). Crystallization of an anti-factor IX antibody and its complex. Acta Crystallogr D Biol Crystallogr 61, 701-3 (IF: 1.4)
6. Rao, Y., Yuan, C., Bian, C., Hou, X., Li, Yongdong., Zhao, G., Ye, X., Huang, Z., & Huang, M.(2006). Crystal Structure of Sar1[H79G]-GDP Which Provides Insight into the Coat-controlled GTP Hydrolysis in the Disassembly of COP II. Chinese J Struct Chem 25, 854-860 (IF: 0.669)
7. Bian C, Yuan C, Zhao G, LI Yongdong, Huang M. (2005) Progress in the Structural Study of Urokinase Receptor System CHINA BIOTECHNOLOGY 25 (B04) 144-7.