hypersensitivity和 allergy的区别
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发布时间:2022-05-14 07:44
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热心网友
时间:2023-10-10 06:37
Hypersensitivity refers to the abnormal adaptive immune response, which is caused by the disorder of tissue physiological function or cell damage ring the process of antigen clearance of the effect procts of adaptive immune response (such as effector T cells, antibodies, etc.). The hypersensitivity includes types I, II, III and IV, each with different pathological characteristics and pathophysiological mechanisms.
Allergy is type I hypersensitivity, also known as rapid type hypersensitivity. The general mechanism is as follows: allergens enter the body for the first time to ince the proction of IgE antibody, which is cytophilic, and combine with Fc receptor on the surface of mast cell and basophil cell membrane to make them enter the sensitization state. After the same allergen enters the body again, it can be cross-linked with IgE on mast cells and basophils in sensitized state, activate mast cells or basophils, make them degranulate, and release biological active media including histamine and leukotriene. The above biological active medium can cause corresponding symptoms when it acts on tissues and organs.
超敏反应是指在免疫应答效应产物(如效应T细胞、抗体等)在抗原清除过程中,造成组织生理功能紊乱或细胞损伤而引起的异常的适应性免疫反应。超敏反应分为Ⅰ型、Ⅱ型、Ⅲ型和Ⅳ型,各有不同的病理特征和病理生理机制。
过敏是Ⅰ型超敏反应,又称速发型超敏反应。其一般机制为:变应原第一次进入人体,诱导产生IgE抗体,即嗜细胞的IgE抗体,并与肥大细胞和嗜碱性细胞膜表面的Fc受体结合,使其进入致敏状态。同一变应原再次进入人体后,可与在致敏状态下的肥大细胞和嗜碱性粒细胞上的IgE交联,激活肥大细胞或嗜碱性粒细胞,使其脱颗粒,释放组胺和白三烯等生物活性介质。上述生物活性介质作用于组织器官时会引起相应的症状。
热心网友
时间:2023-10-10 06:37
hypersensitivity和 allergy的区别
hypersensitivity 这个单词词义是:
n.超敏性
allergy 这个单词词义是:
n.过敏性反应;反感,厌恶
热心网友
时间:2023-10-10 06:38
allergy是由hypersensitivity引起的临床表现